Experienced Professionals in Scientific, Medical Research, and Technology
Chairman & CEO
David is Founder, Chairman and Chief Executive Officer of Gradalis, Inc. From 2004-2012, Mr. Shanahan served as President of Mary Crowley Cancer Research Centers, a cancer research non-profit specializing in clinical application of gene and immune therapies. Mary Crowley Cancer Centers have treated over 4,500 cancer patients in FDA-approved clinical trials.
He is a named inventor on several U.S. patents and co-author of multiple peer-reviewed publications in the field of molecular therapeutics. Prior to his leadership at Mary Crowley, Mr. Shanahan served as the lead investor and founder of successful enterprises in a wide array of fields, many of which led to successful transactions of portfolio investments in the computer, commercial real estate and agricultural industries.
He obtained a B.S. in Electrical Engineering from Texas A&M University.
Chief Medical Officer
John is a co-founder and Chief Medical Officer at Gradalis. He specializes in medical oncology and hematology and is board certified in internal medicine. He is an Oncologist and currently the Executive Medical Director of University of Toledo's Eleanor N. Dana Cancer Center, and has been exploring therapies for cancer treatments for over 30 years.
Dr. Nemunaitis previously held academic positions at Fred Hutchinson Cancer Research Center and the University of Washington School of Medicine. He is a member of the board of directors of the American Cancer Society of Gene and Cell Therapy and is on the editorial board of several peer reviewed journals focusing on cancer and molecular sciences. Dr. Nemunaitis has authored 413 peer-reviewed publications and 44 book chapters.
Dr. Nemunaitis received an M.D. from Case Western Reserve University School of Medicine, Ohio. He completed training in internal medicine at Boston City Hospital and a fellowship in oncology and hematology at University of Washington School of Medicine and Fred Hutchinson Cancer Research Center in Seattle.
Chief Operating Officer
Ernie is Gradalis' Chief Operating Officer. Prior to Gradalis, Ernie was General Manager of Dendreon Corporation’s manufacturing facility in Hanover, New Jersey which was developed to meet the anticipated clinical and commercial manufacturing needs for PROVENGE® (sipuleucel-T) and other active immunotherapy product candidates in development.
Prior to Dendreon, Ernie served as Vice President of Manufacturing at Apptec Laboratory Services where he managed and grew a mammalian cell-based contract manufacturing business unit. Prior to that, he was Senior Director Commercial Manufacturing for ImClone Systems Inc., where he managed a biopharmaceutical start-up operation that produced the company's monoclonal antibody, ERBITUX® (cetuximab) Injection for the treatment of colorectal cancer.
Ernie also served as Manufacturing Head at Baxter Healthcare's Hyland-Immuno Division for the production of Recombinate® (FactorVIII) and held key manufacturing positions at Cellex Biosciences, Verax, Charles River Biotech, KC Biological and Ayerst Research Laboratories. He received his Bachelor's of Science degree in in vitro cell biology from the State University of New York of Arts and Sciences at Plattsburgh and his Cell Biology Certificate from W. Alton Jones Cell Science Center in Lake Placid, NY.
Vice President, Clinical & Regulatory Operations
Gladice heads up Gradalis' Clinical & Regulatory Operations. She is responsible for leading Gradalis’ project management, clinical, regulatory and data services. She oversees regulatory clinical research projects, safety reporting for oncology, and provides the project team with guidance, training and strategic planning.
Ms. Wallraven brings in 20 years of experience in oncology research. Prior to joining Gradalis, Ms. Wallraven held senior regulatory affairs roles Mary Crowley Cancer Research and US Oncology.
She is an active member of the Association of Clinical Research Professionals. Ms. Wallraven has a Bachelor of Science Degree in Biology from Southwestern University.
Sr. Director - Medical and Scientific Affairs
Luisa is Gradalis' Senior Director of Medical and Scientific Affairs where she focuses on early phase single-agent, combination studies, and translational research in immuno-oncology. She completed her medical training in Germany. Luisa has considerable research experience in autoimmune diseases (experimental studies) and the development & clinical testing of engineered autologous tumor cell approaches for cancer.
Vice President - Corporate Development
Walter leads Gradalis' business strategy, corporate development, business development, partnerships, branding, marketing, investor relations, corporate communications, information technology and manufacturing and clinical supply chain functions.
He brings 24 years of management consulting, strategy and technology experience across life sciences, manufacturing, media & marketing industries. He previously worked for Accenture and PricewaterhouseCoopers as well as boutique consulting and financial advisory firms.
He graduated from McCombs Graduate School of Business at The University of Texas at Austin with a Master's in Professional Accounting - Taxation and a Bachelor's in Business Administration - Accounting.
Chief Financial Officer